摘要 |
Compounds of the formula <IMAGE> wherein R1-is hydrogen, alkyl of 1 to 6 carbon atoms or benzyl; R2-is alkyl of 1 to 6 carbon atoms, cycloalkyl of 5 to 7 carbon atoms or, together with R1 and the adjacent nitrogen atom, pyrrolidino, piperidino, hexamethyleneimino, morpholino or N'-methyl-piperazino, where each of the heterocycles may have one or two alkyl of 1 to 3 carbon atoms or one or two methoxy substituents attached thereto; R3,-R4 and R5 are each hydrogen or methyl; R6-is alkyl of 1 to 4 carbon atoms; and A-is alkylene of 2 to 4 carbon atoms; AND NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THEIR SALTS ARE USEFUL AS BRONCHOSPASMOLYTICS AND BRONCHOSECRETOLYTICS. |