摘要 |
<P>PROBLEM TO BE SOLVED: To provide an optically-active spiro-bisisooxazole derivative and its manufacturing method, and an asymmetric catalytic reaction using its metal complex. <P>SOLUTION: A spiro-bisisooxazole derivative expressed by formula (1) and its optically active substance are provided. Provided that, in the formula, n is an integer of 0-3; and R<SP>1</SP>shows hydrogen, a 1-4C alkyl group, a 2-4C alkenyl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted aryl group. <P>COPYRIGHT: (C)2006,JPO&NCIPI |