发明名称 |
METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS |
摘要 |
A pharmaceutical composition which comprises a therapeutically effective amount of an aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at about 12 hours and the use of the composition to treat various neurological diseases, including multiple sclerosis. A method of selecting individuals based on responsiveness to a treatment, including, for example, identifying individuals who responded to treatment with a sustained release fampridine composition. |
申请公布号 |
WO2005099701(A3) |
申请公布日期 |
2006.03.23 |
申请号 |
WO2005US12427 |
申请日期 |
2005.04.11 |
申请人 |
ACORDA THERAPEUTICS, INC.;BLIGHT, ANDREW, R.;MARINUCCI, LAWRENCE;COHEN, RON |
发明人 |
BLIGHT, ANDREW, R.;MARINUCCI, LAWRENCE;COHEN, RON |
分类号 |
A61K31/44 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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