发明名称 Interaction detecting method and bioassay device, and bioassay-use substrate
摘要 In a cell detecting part ( 2 ), and end face ( 13 a) of a cantilever ( 13 ) is previously surface treated so that a detecting nucleotide chain D can be fixed thereto. In a reaction area ( 10 ), and electric field is generated by a cathode ( 11 ) and an anode ( 12 ). A target nucleotide chain T dripped from a nozzle ( 3 ) moves to the end face ( 13 a) while the target nucleotide chain T is stretched. When the detecting nucleotide chain D and the target nucleotide chain T are hybridized, the mass of the cantilever ( 13 ) is increased to lower a natural frequency. Thus, ac voltage is applied to the cantilever ( 13 ) to measure the change of the natural frequency. Thus, whether or not there is the hybridization is detected and the number of the hybridized target nucleotide chains T is quantitatively detected.
申请公布号 US2006063153(A1) 申请公布日期 2006.03.23
申请号 US20050529949 申请日期 2005.04.01
申请人 发明人 MAMINE TAKAYOSHI;KINOSHITA TAKASHI
分类号 C12Q1/68;C12M1/00;C12M1/34;C12N15/09;G01N27/00;G01N33/53;G01N37/00;G01Q10/00;G01Q60/24;G01Q80/00 主分类号 C12Q1/68
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