METHODS FOR IDENTIFYING A PATIENT AS A CANDIDATE FOR TREATMENT WITH A LONG ACTING BETA AGONIST AND FOR PREDICTING A PATIENT'S RESPONSE TO LONG ACTING BETA2 AGONIST THERAPY BY ANALYSING POLYMORPHISMS IN THE BETA2-ADRENERGIC RECEPTOR GENE

摘要

The invention relates to a method for identifying a patient as a candidate for treatment with a long acting beta agonis comprises isolating a biological sample from a patient an identifying the presence or absence of at least one haplotyp C in the beta2 -adrenergic receptor gene. The presence of a least one haplotype C in a patient sample indicates tha patient is a good candidate for treatment. For example, th patient may have a respiratory disease, preferably a obstructive airway disease, and most preferably, COPD o asthma. The invention also related to a method for predictin an asthma patient's response to long acting beta2 agonis therapy comprising detecting polymorphisms in the beta2 adrenergic receptor gene.