| 摘要 |
<p>The invention relates to derivatives of indole-3-carboxamide having general formula (I): wherein: R<SUB>1 </SUB>represents a C<SUB>3</SUB>-C<SUB>10 </SUB>alkyl, a C<SUB>5</SUB>-C<SUB>10 </SUB>carbocyclic radical that is unsubstituted or substituted one or more times with a methyl group; R<SUB>2 </SUB>represents a hydrogen atom or a (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl group; R<SUB>3 </SUB>represents a halogen atom or a (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl group; R<SUB>4 </SUB>represents a hydrogen or halogen atom or a (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl group; R<SUB>5 </SUB>represents a (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl group or a trifluoromethyl; X represents a sulfur atom, an -NHSO<SUB>2</SUB>- group or an -SO<SUB>2</SUB>- group; and n is equal to 2 or 3. The invention also relates to a method of preparing the aforementioned derivatives and to the application of same in therapeutics.</p> |
