| 发明名称 |
ACRYLAMIDE DERIVATIVE |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a compound that can be used for treatment of various kinds of diseases in which CCR3 takes part. SOLUTION: For instance, an acrylamide derivative expressed by N-ä1-[(6-fluoronaphthalen-2-yl)methyl]pyrrolidin-3-yl}-2-[1-(1H-indol-4-yl carbonyl)piperidin-4-iridene] acetamide, or the like having at least three cyclic groups has good CCR3 antagonism, and is effective for medical treatment of diseases in which the CCR3 takes part such as asthma. COPYRIGHT: (C)2006,JPO&NCIPI |
| 申请公布号 |
JP2006076884(A) |
申请公布日期 |
2006.03.23 |
| 申请号 |
JP20030091009 |
申请日期 |
2003.03.28 |
| 申请人 |
ASTELLAS PHARMA INC;TORAY IND INC |
发明人 |
MORIHIRA KOICHIRO;KUBOTA KOICHI;SATO IPPEI;TAKARAKATA TATSUAKI;YOKOTA MASAKI;IMAOKA TAKAYUKI |
| 分类号 |
C07D401/12;A61K31/439;A61K31/4439;A61K31/454;A61K31/4545;A61K31/4709;A61P1/04;A61P11/00;A61P17/00;A61P27/14;A61P29/00;A61P31/18;A61P37/02;A61P37/08;A61P43/00;C07D401/14;C07D413/14;C07D471/04;C07D471/08 |
主分类号 |
C07D401/12 |
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