摘要 |
The invention relates to in vivo imaging agents, specifically radiolabelled insulin derivatives of formula (III); wherein X is -CO-NH- , -NH- , -O-, -NHCONH-, or -NHCSNH-, and is preferably -CO-NH- , -NH- or -O- ; Y is H, alkyl or aryl substituents; R* is a radiolabel moiety suitable for detection by SPECT or PET; and methods for preparing the same as well as their use in in vivo imaging methods. |
申请人 |
HAMMERSMITH IMANET LTD;AMERSHAM HEALTH AS;GLASER, MATTHIAS, EBERHARD;BRADY, FRANK;LUTHRA, SAJINDER, KAUR;CUTHBERTSON, ALAN;KARLSEN, HEGE |
发明人 |
GLASER, MATTHIAS, EBERHARD;BRADY, FRANK;LUTHRA, SAJINDER, KAUR;CUTHBERTSON, ALAN;KARLSEN, HEGE |