发明名称 |
[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLUREA DERIVATIVE AND USE THEREOF |
摘要 |
Novel [1,2,4]triazolo[1,5-a]pyrimidine derivative of the general formula (1): (1) its prodrug or a pharmaceutically acceptable salt thereof, which exhibits an antigen presentation inhibiting activity and is useful as a preventive and/or therapeutic agent for immunological rejection and/or graft versus host reaction in organ/bone marrow transplant, autoimmune disease, allergic disease and/or inflammatory disease and also useful as an anticancer drug or as an immunological tolerance inducer for transplanted organ/transplanted bone marrow.
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申请公布号 |
KR20060026033(A) |
申请公布日期 |
2006.03.22 |
申请号 |
KR20057023187 |
申请日期 |
2005.12.02 |
申请人 |
NIPPON KAYAKU KABUSHIKI KAISHA |
发明人 |
MASUDA AKIRA;SATOH YOSHITAKA;AKIYAMA YUJI;SAIGA KAN;TOYODA ERIKO |
分类号 |
C07D487/04;A61K31/519;A61K31/5377;A61P1/00;A61P1/04;A61P3/10;A61P7/04;A61P7/06;A61P11/06;A61P13/12;A61P17/00;A61P21/04;A61P25/00;A61P29/00;A61P35/00;A61P37/06;A61P37/08;A61P43/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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