IMMUNOGENIC COMPOSITIONS COMPRISING MULTIPLE GONOCOCCAL ANTIGENS

摘要

N. gonorrhoeae is a bacterial pathogen which causes diseases including gonorrhoea, urethritis, cervicitis and pelvic inflammatory disease. In addition, like other inflammatory SYDs, infection is believed to enhance HIV transmission. Within the many proteins of the gonococcal *enome, six have been found to be particularly suitable for immunisation purposes, particularly', when used in combinations. The invention therefore provides a composition comprising two or more of the following antigens: ( 1 ) OmpA; ( 2 ) OmpH; ( 3 ) PPIase; ( 4 ) ngs 41 ; (5) ngsl 17 ; and ( 6 )', App.