发明名称 |
A NOTOGINSENG SAPONIN INTRAVENOUS INJECTION AND THE METHOD FOR PREPARING THIS INJECTION |
摘要 |
<p>The invention shows the saponins family of Radix notoginshen intravenous injection, a method for preparation thereof. The object is to provide an intravenous injection for prevention and treatment of cardiac and cerebral vascular disease and its sequelae. This injection has stable pH, could be used in large dosage, and with main active component of saponins family of Radix notoginshen. The main components for this injection includes saponins family of Radix notoginshen with a concentration of 0.1mg-14.0mg (Rgl), iso-osmotic solution with a concentration of 7.5-9.6mg/ml, and pH stabilizer with a concentration of 0.2-0.5mg/ml. The solvent for said injection is distilled water. The method for preparation of the saponins family of Radix notoginshen intravenous injection includes: (1) dissolution of iso-osmotic solution in distilled water to a concentration of 50-300mg/ml, and filtration through active carbon; (2) addition of the saponins family of Radix notoginshen intravenous injection to the filtrate to a concentration of 0.1 mg-14.0mg (Rgl); (3) addition of pH stabilizer to the filtrate to a concentration of 0.2-0.5mg/ml, filtration until clear, packaging and obtaining of the saponins family of Radix notoginshen intravenous injection.</p> |
申请公布号 |
EP1637152(A1) |
申请公布日期 |
2006.03.22 |
申请号 |
EP20040729596 |
申请日期 |
2004.04.27 |
申请人 |
LI MIN PHARMACEUTICAL FACTORY OF LIVZON PHARMACEUTICAL |
发明人 |
XIE, WEIHONG;LIU, XUEHUA;CHEN, MAORU |
分类号 |
A61K36/258;A61K31/704;A61P9/10;(IPC1-7):A61K36/00 |
主分类号 |
A61K36/258 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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