发明名称 |
Automated method for setting up multiple crystallization experiments in submicroliter volumes |
摘要 |
A method is provided for performing array microcrystallizations to determine suitable crystallization conditions for a molecule, the method comprising: forming an array of microcrystallizations, each microcrystallization comprising a drop comprising a mother liquor solution whose composition varies within the array and a molecule to be crystallized, the drop having a volume of less than 1 microliter; storing the array of microcrystallizations under conditions suitable for molecule crystals to form in the drops in the array; and detecting molecule crystal formation in the drops by taking images of the drops. |
申请公布号 |
US7015041(B2) |
申请公布日期 |
2006.03.21 |
申请号 |
US20020334336 |
申请日期 |
2002.12.31 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
SANTARSIERO BERNARD D.;STEVENS RAYMOND C.;SCHULTZ PETER G.;JAKLEVIC JOSEPH M.;YEGIAN DEREK T.;CORNELL EARL W.;NORDMEYER ROBERT A. |
分类号 |
G01N31/00;G01N33/68;B01D9/02;B01J19/00;B01L3/00;B01L3/02;C07K1/00;C12M1/34;C30B7/00;C30B29/58;C40B40/10;C40B60/14;C40B70/00;G01N1/40 |
主分类号 |
G01N31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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