发明名称 |
Intravascular delivery of nucleic acid |
摘要 |
Disclosed is a process for providing for expression of an exogenous nucleic acid in an extravascular parenchymal cell of a mammal. The nucleic acid is inserted into a vessel of a mammal and the permeability of the vessel is increased. Increasing permeability of the vessel allows delivery of the nucleic acid to an extravascular parenchymal cell.
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申请公布号 |
US7015040(B2) |
申请公布日期 |
2006.03.21 |
申请号 |
US20040008856 |
申请日期 |
2004.12.10 |
申请人 |
MIRUS BIO CORPORATION |
发明人 |
WOLFF JON A.;BUDKER VLADIMIR G.;HAGSTROM JAMES E.;HEGGE JULIA;HERWEIJER HANS |
分类号 |
C12N15/88;A61K38/12;A61K48/00;C12N15/87 |
主分类号 |
C12N15/88 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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