| 发明名称 |
Process for the production of 9-(Z)-retinoic acid |
| 摘要 |
A process for the production of 9-(Z)-retinoic acid is described which comprises reacting an alkali metal salt of 3-methyl-4-oxocrotonic acid with a C<SUB>15</SUB>-triphenyl-phosphonium salt. 9-(Z)-retinoic acid is used in the treatment of dermatological diseases.
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| 申请公布号 |
US7015353(B2) |
申请公布日期 |
2006.03.21 |
| 申请号 |
US20040819693 |
申请日期 |
2004.04.07 |
| 申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
SOUKUP MILAN;THOMESSEN ROLF |
| 分类号 |
C07C61/22;A61K31/203;C07C62/30;C07C403/20 |
主分类号 |
C07C61/22 |
| 代理机构 |
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代理人 |
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| 地址 |
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