| 摘要 |
Provided are 5-membered heterocycle-based p38 kinase, including p38 kinase, including p38alpha and p38beta kinase, inhibitors. Pharmaceutical compositions containing the compounds are also provided. Method of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.
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