发明名称 NOVEL SPIROINDOLINE OR SPIROISOQUINOLINE COMPOUNDS, METHODS OF USE AND COMPOSITIONS THEREOF
摘要 The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles) which act as ligands for the a7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof. Formulas (I, II, III, IV).
申请公布号 WO2005063745(A3) 申请公布日期 2006.03.16
申请号 WO2004US43609 申请日期 2004.12.22
申请人 ARENA PHARMACEUTICALS, INC.;BOATMAN, DOUGLAS, P.;ADAMS, JOHN, W.;MOODY, JEANNE, V.;BABYCH, ERIC, D.;SCHRADER, THOMAS, O. 发明人 BOATMAN, DOUGLAS, P.;ADAMS, JOHN, W.;MOODY, JEANNE, V.;BABYCH, ERIC, D.;SCHRADER, THOMAS, O.
分类号 C07D471/10;A61K31/40;A61K31/47;A61P9/00;A61P25/00;G01N33/68;G01N33/94 主分类号 C07D471/10
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