MRI IMAGING AND CONTRAST METHOD

摘要

A novel MRI contrast technique enables to observe tissue properties not observable by previously known MRI methods. A difference between two disclosed pulse sequences is used to measure magnetization exchange time between water molecules and macromolecules such as proteins, thereby producing a measure highly sensitive to tissue changes resulting from coagulation, yet relatively insensitive to temperature fluctuations. This result is applied to an imaging method and provides direct visualization of the effects of surgical thermal ablation procedures