| 摘要 |
Disclosed are methods for isolating and identifying structuremers that specifically associate with non-nucleic acid target molecules. Each such structuremer species preferably minimally comprises a nucleic acid mimic capable of hybridizing to a substantially complementary single-stranded nucleic acid molecule under stringent hybridization conditions. Structuremers may also include tags to facilitate separation from other reaction components. Structuremer molecules identified by these methods will find application in many fields, including therapeutics and diagnostics. |
