发明名称 |
Methods for treatment of thiol-containing compound deficient conditions |
摘要 |
Methods for therapy of cystic fibrosis and other conditions are provided. The methods comprise one or more agents capable of increasing thiol-containing compound transport via a transporter system (i.e. ABC transporters such as MDR-1 or MRP-2) in cells. Other embodiments include the use of agents to modulate transport of thiol-containing compounds within the cell. Therapeutic methods involve the administration of such agents to a patient afflicted with cystic fibrosis and/or another condition responsive to stimulation of thiol-containing compound transport. |
申请公布号 |
US2006058245(A1) |
申请公布日期 |
2006.03.16 |
申请号 |
US20050211369 |
申请日期 |
2005.08.24 |
申请人 |
NATIONAL JEWISH MEDICAL AND RESEARCH CENTER |
发明人 |
DAY BRIAN J.;SAWYER RICHARD T.;NEWMAN LEE S. |
分类号 |
A61K31/7048;A61K31/35;A61K31/353;A61K31/366;A61K31/37;A61K31/428;A61K31/47;A61K31/537;A61K31/635;A61K31/655 |
主分类号 |
A61K31/7048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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