| 摘要 |
A therapeutic agent-eluting stylet treats a catheter by at least temporarily locating the stylet in a lumen of an indwelling catheter placed into a patient. The therapeutic agent-carrying stylet provides a localized therapeutic effect to the catheter and patient by eluting one or more therapeutic agents directly into the lumen of the catheter, into the fluid within the catheter, into the fluid and tissue in contact with the catheter, and onto the surface of the catheter. By removal and replacement of the temporary stylet from the catheter, renewable therapeutic agent doses can be provided to a component, such as the lumen, of the catheter while the catheter remains within in a patient. One or more therapeutically effective doses of medicated agents can be tailored along the length of the stylet and controlled by the length of time by which the stylet remains installed in the catheter.
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