| 摘要 |
The lipoprotein lipase (LPL) gene is associated with hypertension, elevated plasma triglyceride and metabolic syndrome. A haplotype in the intron 3-intron 4 region (the C/AA/T haplotype), and a haplotype in the intron 5-intron 6 region (the GTAG haplotype), are particularly useful in predicting the risk of an individual for these medical conditions. In addition, other markers that display a linkage disequilibrium with either of these haplotypes can also be used in the same manner. The invention can be applied to Chinese, other Asian populations, Caucasian, African American, and other ethnic groups. |
