发明名称 |
Method of using anti-apoptotic factors in gene expression |
摘要 |
The present invention is directed to methods of prolonging the expression of a heterologous gene (transgene) in a cell, preferably a malignant cell. This method can be used to increase the concentration of a chemotherapeutic agent in a target cellular environment. Preferably, the present invention relates to methods of inhibiting apoptotic cell death to enhance transgene expression, such as gene-directed enzyme/prodrug therapy.
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申请公布号 |
US2006057109(A1) |
申请公布日期 |
2006.03.16 |
申请号 |
US20050509533 |
申请日期 |
2005.05.26 |
申请人 |
WAXMAN DAVID J;SCHWARTZ PAMELA S |
发明人 |
WAXMAN DAVID J.;SCHWARTZ PAMELA S. |
分类号 |
A61K48/00;A61K31/522;A61K31/66;A61K31/7072;C12N9/02 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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