发明名称 |
ANTI-A33 ANTIBODY |
摘要 |
<p>It is intended to provide an antibody or a fragment of the antibody which can bind to A33, specifically attacks a tumor cell expressing A33 by using an immune system with ADCC or CDC and produces no HAHA; and a drug for preventing or treating presently intractable malignant tumors of various types such as solid tumor which contains the antibody or the antibody fragment as described above. Namely, an antibody capable of binding to A33 or a functional fragment thereof which is an A33-binding antibody produced by the hybridoma M10 (deposition number: FERM BP-10107), M96 (deposition number: FERM BP-10108), M165 (deposition number: FERM BP-10106), N26 (deposition number FERM BP-10109), Q47 (deposition number: FERM BP-10104), Q54 (deposition number: FERM BP-10105) or R5 (deposition number: FERM BP-10107) or its functional fragment; and a drug for preventing or treating tumor which contains the above antibody or its functional fragment.</p> |
申请公布号 |
WO2006028197(A1) |
申请公布日期 |
2006.03.16 |
申请号 |
WO2005JP16576 |
申请日期 |
2005.09.02 |
申请人 |
KIRIN BEER KABUSHIKI KAISHA;KATAOKA, SHIRO;TOMURA, TAKAFUMI;OTANI, NORIKO |
发明人 |
KATAOKA, SHIRO;TOMURA, TAKAFUMI;OTANI, NORIKO |
分类号 |
C12N15/09;A61K39/395;A61P35/00;C07K16/30;C12N5/10;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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