Methods for detection of nucleic acid sequences in urine

摘要

A method of analysing a target nucleic acid sequence in a urine sample, said method comprising assaying said urine sample for the presence of said target nucleic acid sequence that has crossed the kidney barrier. Also disclosed is a method of analysing a target nucleic acid sequence in a urine sample, said method comprising assaying a fraction of the extracellular nucleic acid in said urine sample for the presence of said target nucleic acid sequence, which fraction is made up of fragments of culceic acids of fewer than about 300 base pairs.