发明名称 Compositions and methods for producing and using homogenous neuronal cell transplants
摘要 Methods of treating individuals suspected of suffering from diseases, conditions or disorders of the Central Nervous System including nerve damage are provided wherein stable, homogeneous post-mitotic human neurons are into the individual's brain or at or near a site of nerve damage. Pharmaceutical compositions of stable, homogeneous post-mitotic human neurons and a pharmaceutically acceptable medium are also disclosed. Methods of generating non-human animal models of human CNS diseases, conditions or disorders by implanting stable, homogeneous post-mitotic human neurons into the brain of a non-human animal are disclosed. Non-human animals eith stable, homogeneous post-mitotic human neurons implanted in their brain are also disclosed.
申请公布号 US7011827(B2) 申请公布日期 2006.03.14
申请号 US20010862204 申请日期 2001.05.22
申请人 TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 发明人 LEE VIRGINIA M.-Y.;TROJANOWSKI JOHN Q.
分类号 A61K35/00;A01K67/027;A61K35/12;A61K35/30;A61K48/00;C12N5/0793 主分类号 A61K35/00
代理机构 代理人
主权项
地址