摘要 |
FIELD: medicine. ^ SUBSTANCE: method involves applying intraoperative radiation therapy with rapid electrons of 6 MeV with single dose of 8 Gray per removed tumor bed. Then, postoperative remote gamma-therapy course is applied after having healed the wound and removing sutures to postoperative suture region and regional lymph discharge zone at a dose of 2 Gray with 5 fractions per week. The number of remote gamma-therapy sessions is calculated from formula N=8.8(3.4-X-0.169), where N is the number of postoperative remote gamma-therapy sessions; X is the time interval length in days between the intraoperative radiation therapy session and remote gamma-therapy session under condition that mixed irradiation dose (intraoperative radiation therapy and remote gamma-therapy) to thyroid gland tumor region or cancer recurrence area is equal to 60 Gray in terms of isoeffect. ^ EFFECT: increased total course dose per tumor focus; reduced risk of relapse; accelerated treatment course. ^ 1 tbl
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