| 发明名称 |
HYBRID QA MOLECULES WHEREIN Q IS AN AMINOQUINOLINE AND A IS AN ANTIBIOTIC RESIDUE, THEIR SYNTHESIS AND THEIR USES AS ANTIBACTERIAL AGENT |
| 摘要 |
The invention concerns an aminoquinoline-antibiotic hybrid compound of general formula (I): Q-(Y<SUB>1</SUB>)<SUB>p</SUB>-(U)<SUB>p'</SUB>-(Y<SUB>2</SUB>)<SUB>p''</SUB>-A; wherein Q represents an aminoquinoline, (Y<SUB>1</SUB>)<SUB>p</SUB>-(U)<SUB>p'</SUB>-(Y<SUB>2</SUB>)<SUB>p''</SUB> is an optional spacer and A is an antibiotic residue. The invention enables the antibiotic residue activity to be unexpectedly enhanced. |
| 申请公布号 |
WO2006024741(A2) |
申请公布日期 |
2006.03.09 |
| 申请号 |
WO2005FR01937 |
申请日期 |
2005.07.26 |
| 申请人 |
PALUMED S.A.;) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS;SANCHEZ, MURIEL;MEUNIER, BERNARD |
发明人 |
SANCHEZ, MURIEL;MEUNIER, BERNARD |
| 分类号 |
C07D499/76;A61K31/4709;A61P31/04;C07D215/56;C07D401/12;C07D401/14;C07D499/48;C07D499/54;C07D499/64;C07D501/00;C07D501/34;C07K5/00 |
主分类号 |
C07D499/76 |
| 代理机构 |
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