| 发明名称 |
PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- [(4- ETHINYL- PHENYL) - AMID]- 2- [(PHENYL)- AMID] DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS. |
| 摘要 |
<p>The invention relates to novel compounds of formula (I), wherein R, R1, R2 and R3 have the meaning cited in patent claim 1. Said compounds are inhibitors of coagulation factor Xa and can be used in the prophylaxis and/or therapy of thromboembolic diseases and in the treatment of tumors.</p> |
| 申请公布号 |
MXPA05013536(A) |
申请公布日期 |
2006.03.09 |
| 申请号 |
MX2005PA13536 |
申请日期 |
2004.05.27 |
| 申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG. |
发明人 |
JOHANNES GLEITZ |
| 分类号 |
A61K31/4025;A61K31/401;A61P7/02;A61P9/10;A61P25/06;A61P29/00;A61P35/00;C07C275/26;C07D401/12;C07D403/12;C07D413/12;(IPC1-7):A61K31/402 |
主分类号 |
A61K31/4025 |
| 代理机构 |
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代理人 |
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