| 发明名称 |
LOCALIZATION AND CHARACTERIZATION OF FLAVIVIRUS ENVELOPE GLYCOPROTEIN CROSS-REACTIVE EPITOPES AND METHODS FOR THEIR USE |
| 摘要 |
<p>Disclosed herein is a method for identifying flavivirus cross-reactive epitopes. Also provided are flavivirus E-glycoprotein cross-reactive epitopes and flavivirus E-glycoprotein cross-reactive epitopes having reduced or ablated cross-reactivity (and polypeptides comprising such epitopes), as well as methods of using these molecules to elicit an immune response against a flavivirus and to detect a flaviviral infection.</p> |
| 申请公布号 |
CA2576798(A1) |
申请公布日期 |
2006.03.09 |
| 申请号 |
CA20052576798 |
申请日期 |
2005.07.27 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SE CRE;THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE DEPARTM |
发明人 |
CRILL, WAYNE D.;CHANG, GWONG-JEN J. |
| 分类号 |
C12N15/10;A61K39/12;C07K14/18;G01N33/569 |
主分类号 |
C12N15/10 |
| 代理机构 |
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