PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

摘要

A piperidine derivative in which the piperidine ring is bonded in the 4-position to a monosubstituted or unsubstituted (-R<SUP>1</SUP>) benzene ring through vinylene and has an acyl group (-C(=O)-R<SUP>4</SUP>) in the 1-position; or a pharmaceutically acceptable salt of the derivative. The derivative and salt are excellent in sodium channel inhibitory activity and analgetic activity and have a high analgetic effect especially on neurogenic pains. The compounds are useful as a sodium channel inhibitor reduced in side effects.