发明名称 |
Live attenuated vaccine against porcine pleuropneumonia |
摘要 |
The present invention provides a method for obtaining an immunogenic, non-haemolytic strain of Actinobacillus pleuropneumoniae which is modified, at least in a segment of the apxIA gene and optionally in a segment of the apxIIA gene that encodes a transmembrane domain of the Apx haemolytic and cytolytic exotoxins. It comprises also the strains, and the attenuated live vaccine porcine pleuorpneumonia obtained therewith.
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申请公布号 |
US2006051371(A1) |
申请公布日期 |
2006.03.09 |
申请号 |
US20050535416 |
申请日期 |
2005.05.19 |
申请人 |
RIBAS JAUME P;BRU VIRGILI SERGI;ESPUNA MASO ENRIC;QUEROL MURILLO ENRIQUE |
发明人 |
RIBAS JAUME P.;BRU VIRGILI SERGI;ESPUNA MASO ENRIC;QUEROL MURILLO ENRIQUE |
分类号 |
A61K39/02;A61K39/102;C07K14/285;C12N1/21;C12N1/36;C12N15/74 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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