发明名称 PYRIMIDINYLPYRAZOLES AS TGF-BETA INHIBITORS
摘要 <p>The invention is based on the discovery that compounds of formula (I) possess high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. The invention features a compound of formula (I) and uses thereof: formula (I).</p>
申请公布号 WO2006026305(A1) 申请公布日期 2006.03.09
申请号 WO2005US30132 申请日期 2005.08.24
申请人 BIOGEN IDEC MA INC;LEE, WEN-CHERNG;SUN, LIHONG;CHUAQUI, CLAUDIO;CORNEBISE, MARK;SINGH, JUSWINDER;SHAN, FENG 发明人 LEE, WEN-CHERNG;SUN, LIHONG;CHUAQUI, CLAUDIO;CORNEBISE, MARK;SINGH, JUSWINDER;SHAN, FENG
分类号 (IPC1-7):C07D401/14;A61P35/00;C07D405/14;C07D471/04;C07D403/14;A61K31/506 主分类号 (IPC1-7):C07D401/14
代理机构 代理人
主权项
地址