发明名称 2-AMINOPYRIMIDINE DERIVATIVES AS RAF KINASE INHIBITORS.
摘要 <p>This application discloses compounds that inhibit Raf kinase having the formula (I), wherein R1 is a phenyl radical or a heteroaryl radical; and R2 is a phenyl radical; or an N-oxide or a pharmaceutically acceptable salt thereof. The compounds are useful for the treatment of proliferative diseases, such as cancer.</p>
申请公布号 MXPA05013349(A) 申请公布日期 2006.03.09
申请号 MX2005PA13349 申请日期 2004.06.11
申请人 NOVARTIS AG. 发明人 MICHAEL LLOYD SABIO
分类号 A61K31/505;A61K31/506;A61P35/00;C07D239/42;C07D401/04;C07D401/14;C07D403/04;C07D417/04;(IPC1-7):A61K31/505 主分类号 A61K31/505
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