发明名称 |
MONOCARBOXYLATE TRANSPORTERS EXPRESSED IN CANCER CELLS |
摘要 |
MCT1 and MCT4 are expressed at higher levels in many cancer cells than comparable normal cells of the same tissue. Disclosed herein are assays for determining whether a test material/molecule is a substrate for, and/or is actively transported by, the MCT1 and/or MCT4, as well as inhibitors and substrates of MCT1 and/or MCT4, methods of isolating the same, and methods of using the same for treatment or diagnosis of cancer. |
申请公布号 |
WO2005098444(A3) |
申请公布日期 |
2006.03.09 |
申请号 |
WO2004US21629 |
申请日期 |
2004.07.06 |
申请人 |
XENOPORT, INC.;ZERANGUE, NOA;BHAT, LAXMINARAYAN |
发明人 |
ZERANGUE, NOA;BHAT, LAXMINARAYAN |
分类号 |
A61K31/195;C07K14/705;G01N33/50;G01N33/574;G01N33/68;G01N33/84 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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