<p>It is intended to provide a preparation for external use which can enhance the skin permeability of a hydrophilic drug such as NSAID so that it can act directly on an affected site without passing through digestive tracts or mucosa. This external preparation of the S/O type, which comprises a drug-containing complex dissolved or dispersed in an oily phase, is characterized in that in the complex, a hydrophilic drug is coated with a surfactant. It is highly excellent in transdermal absorbability.</p>
