| 摘要 |
<p>The specification discloses modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; polynucleotide molecules encoding modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; and method of producing modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain.</p> |
| 申请人 |
ALLERGAN, INC.;LI, SHENGWEN;STEWARD, LANCE, E.;FERNANDEZ-SALAS, ESTER;GILMORE, MARCELLA, A.;FRANCIS, JOSEPH, A.;AOKI, KEI, ROGER |
发明人 |
LI, SHENGWEN;STEWARD, LANCE, E.;FERNANDEZ-SALAS, ESTER;GILMORE, MARCELLA, A.;FRANCIS, JOSEPH, A.;AOKI, KEI, ROGER |
