| 发明名称 |
1-(Pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives |
| 摘要 |
The present invention is directed to 1-pyrrolidin-1-ylmethyl-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives that modulate the activity of protein kinases ("PKs"). Pharmaceutical compositions comprising these compounds, methods of treating diseases related to abnormal PK activity utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.
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| 申请公布号 |
US7008943(B2) |
申请公布日期 |
2006.03.07 |
| 申请号 |
US20030429895 |
申请日期 |
2003.05.05 |
| 申请人 |
PHARMACIA & UPJOHN COMPANY |
发明人 |
MOON MALCOLM WILSON;MOROZOWICH WALTER;GAO PING |
| 分类号 |
A61K31/5375;C07D401/06;A61K31/404;A61K31/4045;A61K31/4439;A61K31/496;A61K31/661;A61P1/00;A61P1/16;A61P3/00;A61P3/10;A61P7/02;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P19/04;A61P25/00;A61P25/28;A61P29/00;A61P31/00;A61P31/04;A61P35/00;A61P37/00;A61P37/06;A61P43/00;C07D401/14;C07D403/06;C07D403/14;C07D413/02;C07F9/572;C07F9/6558 |
主分类号 |
A61K31/5375 |
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