发明名称 Quaternary ammonium compounds
摘要 A compound of formula corresponding to either formula (Ia) or (Ib): wherein: M represents a molecule that can be used for the treatment or diagnosis of pathologies caused by attack on the cartilage, R<SUB>1</SUB>, R<SUB>2 </SUB>and R<SUB>3 </SUB>represent alkyl, or R<SUB>1</SUB>, R<SUB>2 </SUB>and R<SUB>3 </SUB>together with the nitrogen atom carrying them, form a heterocycle, X represents a (C<SUB>1</SUB>-C<SUB>6</SUB>)alkylene chain in which one or more -CH<SUB>2</SUB>- groups are optionally replaced by sulphur, oxygen, or -NR-, -CO-, -CO-NH-, -CO<SUB>2</SUB>-, -SO- or -SO<SUB>2</SUB>-, n represents 0 or 1, Hal represents halogen, or, R<SUB>4 </SUB>represents alkyl, Hal represents halogen, represents a molecule that can be used for the treatment or diagnosis of pathologies caused by attack on the cartilage, wherein the nitrogen atom may optionally be included in a saturated or unsaturated nitrogen-containing heterocyclic system, or included in a double bond.
申请公布号 US7008613(B2) 申请公布日期 2006.03.07
申请号 US20040843906 申请日期 2004.05.12
申请人 LES LABORATOIRES SERVIER 发明人 MADELMONT JEAN-CLAUDE;GIRAUD ISABELLE;NICOLAS COLETTE;MAURIZIS JEAN-CLAUDE;RAPP MARYSE;OLLIER MONIQUE;RENARD PIERRE;CAIGNARD DANIEL-HENRI
分类号 C07D279/02;A61K31/165;A61K31/4045;A61K31/5415;A61K31/555;A61K31/7008;A61K49/00;A61K51/00;A61P19/00;C07C231/12;C07C237/20;C07D259/00;C07D409/06;C07D417/12;C07F13/00;C07H5/06;C07H15/12 主分类号 C07D279/02
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