A METHOD FOR ISOLATING 1,3-PROPANEDIOL OR 1,3-PROPANEDIOL AND 1,2-PROPANEDIOL FROM A SOLUTION CONTAINING 1,3-PROPANEDIOL, 1,2-PROPANEDIOL, GLYCEROL AND GLCUOSE

摘要

A method of isolating 1,3-propanediol from a solution containing 1,3-propanediol, 1,2-propanediol, glycerol, and glucose is provided. The method includes: obtaining a concentrate by concentrating the solution via reduced pressure evaporation; dissolving the concentrate in a solvent selected from the group consisting of ethyl acetate, methyl ethyl ketone, and a mixture thereof and leaving the solution alone to fractionate the compounds in a solvent layer and a water layer; and loading the solvent layer in a silica-filled column under a low pressure liquid chromatography condition and eluting the solvent layer with a mixed solvent of methanol and at least one solvent which is miscible with methanol and has a polarity lower than methanol.