发明名称 Delivery of stimulants through an inhalation route
摘要 The present invention relates to the delivery of stimulants through an inhalation route. Specifically, it relates to aerosols containing stimulants that are used in inhalation therapy. In a method aspect of the present invention, a stimulant is delivered to a patient through an inhalation route. The method comprises: a) heating a coating of a stimulant, on a solid support, to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% stimulant degradation products. In a kit aspect of the present invention, a kit for delivering a stimulant through an inhalation route is provided which comprises: a) a coating of a stimulant drug and b) a device for dispensing said coating a stimulant as a condensation aerosol.
申请公布号 US7008616(B2) 申请公布日期 2006.03.07
申请号 US20040816492 申请日期 2004.04.01
申请人 ALEXZA PHARMACEUTICALS, INC. 发明人 RABINOWITZ JOSHUA D.;ZAFFARONI ALEJANDRO C.
分类号 A61K9/12;A61K9/00;A61K9/14;A61K9/72;A61K31/00;A61K31/13;A61K31/137;A61K31/138;A61K31/165;A61K31/167;A61K31/19;A61K31/192;A61K31/216;A61K31/27;A61K31/40;A61K31/403;A61K31/404;A61K31/4045;A61K31/405;A61K31/407;A61K31/4196;A61K31/421;A61K31/422;A61K31/423;A61K31/437;A61K31/439;A61K31/4402;A61K31/4418;A61K31/4525;A61K31/4545;A61K31/46;A61K31/473;A61K31/48;A61K31/485;A61K31/49;A61K31/495;A61K31/496;A61K31/4985;A61K31/501;A61K31/505;A61K31/519;A61K31/53;A61K31/5415;A61K31/55;A61K31/551;A61K31/5513;A61K31/5517;A61K45/00;A61K47/48;A61M11/00;A61M15/00;A61P15/10;A61P21/02;A61P25/06;A61P25/08;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/32;A61P29/00;A61P31/04;A61P37/08;A61P43/00;C07D471/04;C07D487/04;F24J1/00 主分类号 A61K9/12
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