| 摘要 |
PROBLEM TO BE SOLVED: To provide a separate purifying method for a physiologically active substance under a mild condition, which is a process using a diffusion phenomenon and possible to be applied industrially. SOLUTION: In a separator using a porous membrane, a flat membrane of an average pore diameter of≥2 nm and≤2μm, a porosity of≥40% and≤90% and a membrane thickness of≥30μm and≤1 nm is used and a steady diffusion method using the diffusion phenomenon in pores of the membrane is applied. After making the flat membrane envelope-shaped, piling up a plurality of membranes and filling both ends of them with a resin, both the ends are cut off to make a module openable and penetrable. Structural problems such as a supporter and a clogging, which are conventional problems in filtering, are resolved by molding the flat membrane in the envelope shape and using the pore diffusion method. The flat membrane is excellent in mechanical stability and removal performance of bacteria/viruses as the thickness of the flat membrane can be large, and therefore the physiologically active substance can be separated/purified in industrial scale by using it. COPYRIGHT: (C)2006,JPO&NCIPI
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