SCREENING OF AGENTS FOR ACTIVITY AGAINST ISCHEMIC MYOCARDIAL INSULTS
摘要
<p>Integrin-linked kinase (ILK) and Akt/protein kinase B (PKB) are important mediators of signaling in cardiomyocytes and can both prevent damage and promote healing associated with ischemic injury to the heart. Thus, the present invention provides for methods of screening for agents that increase the expression of ILK and/or Akt/PKB. Methods of treatment based on such agents are also provided.</p>
申请公布号
WO2006023879(A1)
申请公布日期
2006.03.02
申请号
WO2005US29849
申请日期
2005.08.22
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;SRIVASTAVA, DEEPAK;BOCK-MARQUETTE, IIDIKO;SAXENA, ANKUR