METHOD OF DELIVERING RNA INTERFERENCE AND USES THEREOF

摘要

The invention provides a method of RNA interference, which comprises
contacting the cell with a fusion protein-double stranded RNA complex, the
complex comprising the double stranded RNA segment containing a double
stranded RNA of interest and a fusion protein, the fusion protein comprising
(1) a targeting moiety, which will specifically binds to a site on a target
cell, and (2) a binding moiety, which will bind to the double stranded RNA,
wherein the double stranded RNA segment initiates RNA interference in the cell.