| 摘要 |
Novel methods of inhibiting angiogenesis or tumorigenesis or promoting apoptosis with compositions that inhibit the apelin/APJ signaling pathway are provided. Also provided are methods of promoting angiogenesis or inhibiting apoptosis with compositions comprising an apelin polypeptide or small molecule agonist. The present invention further provides methods for identifying therapeutic agents that affect angiogenesis and/or apoptosis.
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