发明名称 |
Novel recombinant sabin type 1 poliovirus vector and vaccine against poliovirus |
摘要 |
The present invention relates to a novel recombinant Sabin type 1 poliovirus vector for the immunogenicity of neutralizing antibody against polioviral infection, which comprises: (a) a genomic nucleotide sequence of a parent Sabin type 1 poliovirus; (b) a nucleotide sequence encoding an additional polioviral cleavage site; and (c) a nucleotide sequence of a conformational epitope encoding a VP1 neutralizing epitope of poliovirus type 2 or 3 and linked to the nucleotide sequence of (b).
|
申请公布号 |
US2006045889(A1) |
申请公布日期 |
2006.03.02 |
申请号 |
US20040926333 |
申请日期 |
2004.08.26 |
申请人 |
BAE YONG SOO;LEE SANG GOO;JEONG HYE R;LEE DONG S;KIM KI T;KIM DAE Y |
发明人 |
BAE YONG SOO;LEE SANG GOO;JEONG HYE R.;LEE DONG S.;KIM KI T.;KIM DAE Y. |
分类号 |
A61K39/13;C12N15/863;C12Q1/68;C12Q1/70 |
主分类号 |
A61K39/13 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|