发明名称 |
METHOD OF DELIVERING RNA INTERFERENCE AND USES THEREOF |
摘要 |
The invention provides a method of RNA interference, which comprises contacting the cell with a fusion protein-double stranded RNA complex, the complex comprising the double stranded RNA segment containing a double stranded RNA of interest and a fusion protein, the fusion protein comprising (1) a targeting moiety, which will specifically binds to a site on a target cell, and (2) a binding moiety, which will bind to the double stranded RNA, wherein the double stranded RNA segment initiates RNA interference in the cell. |
申请公布号 |
WO2006023491(A2) |
申请公布日期 |
2006.03.02 |
申请号 |
WO2005US29111 |
申请日期 |
2005.08.15 |
申请人 |
THE CBR INSTITUTE FOR BIOMEDICAL RESEARCH, INC.;LIEBERMAN, JUDY;SONG, ERWEI |
发明人 |
LIEBERMAN, JUDY;SONG, ERWEI |
分类号 |
A61K48/00;C12N15/11;C12N15/113 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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