<p>A bacterial protein which converts 2-methyl citrate to 2-methyl isocitrate is a previously unknown target for antibacterial agents. The protein of this activity is associated with mucoid bacteria and inhibitors of production or activity of this protein in combination with propionic acid mitigate the virulence of these bacteria.</p>
申请公布号
WO2006022640(A1)
申请公布日期
2006.03.02
申请号
WO2004US24051
申请日期
2004.07.26
申请人
BIOLOGICAL TARGETS, INC.;CANDAS, MEHMET;BULLA, LEE, A.