发明名称 |
NMR-METHOD FOR DETERMINING THE RISK OF DEVELOPING TYPE 2 DIABETES |
摘要 |
<p>Methods for assessing the risk of developing Type 2 diabetes and other related disorders include obtaining an NMR derived reference spectrum for a known glucose concentration sample and storing this information as a reference standard. A patient blood sample is collected and NMR derived patient spectrums for the blood sample are obtained. The two NMR data sets (the reference and the patient) are compared and a glucose concentration is determined for the patient sample. The glucose concentration can be evaluated with a blood sample undergoing lipoprotein cholesterol evaluation. The NMR based test can be used to concurrently provide a glucose concentration and lipoprotein constituent values based on a single testing event. The disclosure also includes a multi-purpose test, i.e., a test which concurrently provides lipoprotein screening and coronary heart disease risk evaluation along with a diabetes screening and risk assessment for developing Type 2 diabetes. A method for assessing diabetes includes identifying the presence of diabetic dyslipidemia based on the values of predetermined NMR measured lipoprotein constituents.</p> |
申请公布号 |
EP1171778(B1) |
申请公布日期 |
2006.03.01 |
申请号 |
EP20000926111 |
申请日期 |
2000.04.19 |
申请人 |
LIPOSCIENCE, INC.;NORTH CAROLINA STATE UNIVERSITY |
发明人 |
OTVOS, JAMES, D.;BENNETT, DENNIS, W. |
分类号 |
G01R33/46;G01N24/08;G01N33/483;G01N33/53;G01N33/66;G01N33/68;G01N33/74;G01R33/465 |
主分类号 |
G01R33/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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