ORALLY IMMUNOGENIC BACTERIAL ENTEROTOXINS EXPRESSED IN TRANSGENIC PLANTS
摘要
The invention provides mutant Escherichia coli heat labile (LT) and Vibrio cholerae toxin (CT) polypeptides and the polynucleotides that encode them. The mutant LT and CT polypeptides can be readily produced in plants and can be used to treat or prevent diseases caused by E. coli and V. cholera. The polypeptides are also useful as adjuvants.
申请公布号
WO0037609(A2)
申请公布日期
2000.06.29
申请号
WO1999US30747
申请日期
1999.12.22
申请人
BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH AT CORNELL;MASON, HUGH, S.;ARNTZEN, CHARLES, J.