METHOD FOR IMMORTALIZING CHICKEN CELLS.

摘要

THIS INVENTION RELATES TO THE INTRODUCTION OF P53 UNDER THE CONTROL OF THE METALLOTHIONEIN PROMOTER INTO PRIMARY CELLS TO PRODUCE IMMORTALIZED CELL LINES. THE CELLS ARE USEFUL AS SUBSTRATES FOR VIRAL PROPAGATION. AS CONTAMINANT-FREE SOURCES FOR RECOMBINANT PROTEIN PRODUCTION. FOR RECOMBINANT VIRUS PRODUCTION AND AS CELL SUBSTRATES TO SUPPORT PRIMARY CELLS AND IMPROVE VIRUS YIELD DURING VIRUS PROPAGATION.